Review of Inflammation-Related Biomarkers for the Prediction of Prognosis in Colorectal Cancer Patients - Yamamoto 2021

This is a brief audio review. In the article Inflammation-Related Biomarkers for the Prediction of Prognosis in Colorectal Cancer Patients published, 2021 by Yamamoto T and Colleagues, The outcomes and key points are as noted: CRC is the world's largest cause of cancer fatalities. Identifying patients with poor prognosis or high recurrence risk allows us to selectively execute intensive treatments such as preoperative and/or postoperative chemotherapy and extended surgery. Inflammation-related prognostic indicators, obtainable from regular blood examination, are useful in many types of cancer, such as neutrophil-lymphocyte ratio, lymphocyte-C-reactive protein ratio, platelet-lymphocyte ratio, and lymphocyte-monocyte ratio. Some scoring methods based on circulating blood cell counts and albumin concentration predict cancer patients' prognosis, such as the Glasgow prognostic score, systemic inflammation score, and prognostic nutritional index. Cancer type affects the effective biomarker and cutoff value. This review summarizes each inflammation-related marker's predictive significance in CRC.

Int J Mol Sci. 2021 Jul 27;22(15):8002. doi: 10.3390/ijms22158002.