Brief Review of Effect on Delay of Levonorgestrel— Piaggio 2010

Written By Rafi Yusuf

This is a brief audio review.

In the article Effect on pregnancy rates of the delay in the administration of levonorgestrel for emergency contraception: a combined analysis of four WHO trials published, 2010 by Piaggio and Colleagues, The outcomes and key points are as noted: Levonogestrel is most effective when given soonest after sex for emergency contraception. Levonorgestrel is most effective within 24 hours (estimated odds ratio 1.0). The efficacy is reduced to a pregnancy odds ratio of 6.0 at 5 days In a Meta-analyses (of 4 randomized controlled trials) with 6794 patients who were Women in 4 World Health Organization randomized controlled trials.

This concludes the brief audio review.

Piaggio G, Kapp N, von Hertzen H. Effect on pregnancy rates of the delay in the administration of levonorgestrel for emergency contraception: a combined analysis of four WHO trials. Contraception. 2011 Jul;84(1):35-9. doi: 10.1016/j.contraception.2010.11.010. Epub 2011 Jan 7. PMID: 21664508.

Rafi Yusuf
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