Brief Review of sFlt-1:PlGF in Suspected Preeclampsia—Zeisler 2016

This is a brief audio review.

In the article Predictive Value of the sFlt-1:PlGF Ratio in Women with Suspected Preeclampsia published, 2016 by Zeisler and Colleagues, The outcomes and key points are as noted: sFlt-1:PlGF ratio of less than 38 predicts the 1 to 4 weeks of preeclampsia in 24 week to 37 week gestation pregnancies. An sFlt-1:PlGF ratio of 38 or lower was predictive of the absence of fetal adverse outcomes within 1 week (negative predictive value 99.3% [95% CI, 97.9 to 99.9]); a ratio greater than 38 was predictive of the presence of these outcomes at 4 weeks (positive predictive value, 47.5% [95% CI, 38.4 to 56.8]). Confidence intervals at 95% for entire data set. In a Observational, prospective, multicenter with 1050 patients who were Pregnant patients 3rd trimester.

This concludes the brief audio review of Predictive Value of the sFlt-1:PlGF Ratio in Women with Suspected Preeclampsia published, 2016 by Zeisler and Colleagues.

Zeisler H, Llurba E, Chantraine F, Vatish M, Staff AC, Sennström M, Olovsson M, Brennecke SP, Stepan H, Allegranza D, Dilba P, Schoedl M, Hund M, Verlohren S. Predictive Value of the sFlt-1:PlGF Ratio in Women with Suspected Preeclampsia. N Engl J Med. 2016 Jan 7;374(1):13-22. doi: 10.1056/NEJMoa1414838. PMID: 26735990.