Impact of social relationships on Alzheimer's memory impairment: mechanistic studies —Hsiao, 2018

This is an audio summary of the article "Impact of social relationships on Alzheimer's memory impairment: mechanistic studies" by Hsiao in 2018. Adverse memory and neuronal loss are the most common forms of dementia in older people. It is expected that the number of people with AD dementia will increase dramatically in the next 30 years, projecting to 75 million in 2030 and 131.5 million in 2050 worldwide. Early studies have shown that social environments, particularly social relationships, can affect one's behavior and mental health, with lonely persons having higher risk of AD. Social activities can help prevent cognitive decline and delay the onset of AD if kept mentally active and frequently participate in social activities. This review focuses on the impact of social behaviors on the progression of cognitive deficit in animal models of AD, with a focus on a mechanistic scheme that explains how social isolation exacerbates cognitive impairment and how social interaction with conspecifics rescues AD patients' memory deficit. This is the end of this informational audio track on the Impact of Social Relationships on Alzheimer's memory impairment: mechanistic studies. 

Hsiao, Y. H., Chang, C. H., & Gean, P. W. (2018). Impact of social relationships on Alzheimer's memory impairment: mechanistic studies. Journal of Biomedical science, 25(1), 3. https://doi.org/10.1186/s12929-018-0404-x