Review of the Study, an Association Between Low-Density Lipoprotein Cholesterol Reduction and Relative and Absolute Effects of Statin Treatment: A Systematic Review and Meta-analysis— Byrne 2022

This is a brief audio review. In the article Evaluating the Association Between Low-Density Lipoprotein Cholesterol Reduction and Relative and Absolute Effects of Statin Treatment: A Systematic Review and Meta-analysis published, 2022 by Byrne and Colleagues, The outcomes and key points are as noted: Statin based medications displayed Absolute risk reductions of major adverse cardiovascular events and mortality that were modest and less than those of relative risk reductions, but still apparent. In a Meta-analysis with 21 patients who were Trials involving involving adults 18 years or older.

Byrne P, Demasi M, Jones M, Smith SM, O'Brien KK, DuBroff R. Evaluating the Association Between Low-Density Lipoprotein Cholesterol Reduction and Relative and Absolute Effects of Statin Treatment: A Systematic Review and Meta-analysis. JAMA Intern Med. 2022 May 1;182(5):474-481. doi: 10.1001/jamainternmed.2022.0134. Erratum in: doi: 10.1001/jamainternmed.2022.1671. PMID: 35285850; PMCID: PMC8922205.