Potential use of serotherapy in the prevention and treatment of infection with the human immunodeficiency virus—Zolla-Pazner 1987

Prophylactic immunization and anti-viral treatment seem like the best ways to prevent and treat HIV, but no safe and effective vaccines or drugs have been developed. Thus, a third method for disease prophylaxis and therapy should be proposed. Passively administering anti-HIV antibodies prevents and slows infection. Discussing xenogeneic and human antibody pros and cons. Cell lines that produce HIV antibodies are needed in big quantities. Summarize these line-making methods. Finally, preliminary data show that HIV-antibody-producing human cell lines are feasible.

Zolla-Pazner, S., Pinter, A., & Mizuma, H. (1987). Potential use of serotherapy in the prevention and treatment of infection with the human immunodeficiency virus. Journal of virological methods, 17(1-2), 45–53. https://doi.org/10.1016/0166-0934(87)90067-x

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Recent advances in the characterization of HIV-1 neutralization assays for standardized evaluation of the antibody response to infection and vaccination—Polonis 2008

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Anti-V2 antibody deficiency in individuals infected with HIV-1 in Cameroon—Liu 2019