Historical Overview of Transplantation — Clyde, 2021

This paper discusses the history of renal transplants, including early attempts and successes, as well as the scientific findings and rivalries that have contributed to the field. The introduction outlines the objective of the paper, which is to provide insight into the evolution of renal transplants. It discusses the initial failures of homografts, as well as subsequent experiments using animal donors. The discussion and conclusion explore the success of Main and Prehn's infusion of donor cells in irradiated mice, and how this inspired further experimentation in human kidney allograft recipients. Additionally, the paper delves into the rivalries between scientists in the field, including those between Alexis Carrel and Charles Guthrie and those between proponents of cellular and humoral immunity.

Barker, C. F., & Markmann, J. F. (2013). Historical overview of transplantation. Cold Spring Harbor perspectives in medicine, 3(4), a014977. https://doi.org/10.1101/cshperspect.a014977